This course thinks with and from Latin America to consider the environmental and ecological conflicts and politics of cuidado (care) emerging across the hemisphere in times of climate crisis and deepening socio-environmental injustice. Latin American thinkers and practitioners have provided innovative conceptual and methodological tools for analyzing, organizing, and acting in defense of territory and life. In this course, we will consider how legacies of colonialism and (neo)extractivism are not only an ongoing curse of the Americas, but also a a condition of possibility for feminist, decolonial, Indigenous, and ecological proposals, such as degrowth, buen vivir, cuerpo-territorio (body-territory), rights of nature, ontological politics, and participatory action research, among other ways of knowing, being, and doing. What can we learn from engagement with the historic and contemporary socioenvironmental challenges occurring across the Spanish and Portuguese-speaking Americas? How are diverse urban and rural communities, technoscientific actors, researchers, and ancestral knowers understanding and responding to the region’s emerging climate and environmental scenarios? What are the possibilities for dialogue, exchange, and problem solving between such diverse actors and their multiple ways of knowing and being that span millennial, colonial, and modernizing temporalities? Throughout the course, we will interrogate and reflect on these questions from the situated perspectives of Latin America and its many territorial realities, ecological relations, and social worlds.